Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0019cpr17 | Gestation Elicited | CPR2013

Application of RNA-seq transcriptomic analysis to reproductive physiology of the pig: Insights into differential trophoblast function within the late gestation porcine placenta

McNeel Anthony K. , Chen Celine , Schroeder Steven , Sonstegard Tad , Dawson Harry , Vallet Jeffrey L.

Next generation DNA sequencing is a high throughput method of sequencing DNA samples in parallel. During the last 10 years, this technology has expanded to include sequencing and quantification of an entire transcriptome. The advantage of this method of transcriptome analysis is that it allows the investigator to detect previously unknown genes and splice variants as well as detect potential DNA polymorphisms. Application of this technology, especially when used to perfo...

bp0008rdr2 | Genomes, Proteomics, Metabolomics | REDR2014

Genetic improvement in cattle — are we sacrificing reproduction in favor of production?

Cushman Robert A , McNeel Anthony K , Tait Jr. Robert G , Lindholm-Perry Amanda K , Perry George A , Snelling Warren M , Bennett Gary L

Summary. Reproductive traits can range from lowly to moderately heritable. Genomic technologies provide a powerful tool for improving selection for traits that are lowly heritable, sex-linked, or not expressed until later in life. Therefore, as genomic technologies become a part of selection decisions, there is a critical need to understand how specific gene variants affect reproductive traits in cattle. Both classical quantitative genetics approaches and geno...